HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Douglas E Vaughan Selected Research

Plasminogen Activator Inhibitor 1

11/2021Role of PAI-1 in hepatic steatosis and dyslipidemia.
2/2021Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484.
1/2021Identification of Cardiac Fibrosis in Young Adults With a Homozygous Frameshift Variant in SERPINE1.
1/2021Inhibition of PAI-1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice.
9/2020Effects of lisinopril treatment on the pathophysiology of PCOS and plasminogen activator inhibitor-1 concentrations in rats.
1/2020Association between plasminogen activator inhibitor-1 in young adulthood and nonalcoholic fatty liver disease in midlife: CARDIA.
12/2019PAI-1 contributes to homocysteine-induced cellular senescence.
12/2018Inhibition of Plasminogen Activator Inhibitor 1 Attenuates Hepatic Steatosis but Does Not Prevent Progressive Nonalcoholic Steatohepatitis in Mice.
8/2017Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-β and Cardiac Fibrosis.
1/2017Generation of human iPSCs from urine derived cells of patient with a novel heterozygous PAI-1 mutation.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Douglas E Vaughan Research Topics

Disease

22Fibrosis (Cirrhosis)
02/2021 - 05/2002
14Thrombosis (Thrombus)
10/2021 - 07/2002
14Myocardial Infarction
07/2014 - 06/2002
13Obesity
11/2021 - 02/2004
13Cardiovascular Diseases (Cardiovascular Disease)
10/2021 - 03/2005
10Inflammation (Inflammations)
07/2020 - 04/2005
9Hypertension (High Blood Pressure)
11/2021 - 06/2002
7Insulin Resistance
11/2021 - 08/2002
5Cardiomegaly (Heart Hypertrophy)
01/2019 - 02/2005
4Infections
07/2020 - 11/2016
4Heart Failure
08/2017 - 04/2006
4Type 2 Diabetes Mellitus (MODY)
09/2014 - 04/2005
3Neoplasms (Cancer)
02/2021 - 05/2007
3Cardiomyopathies (Cardiomyopathy)
01/2021 - 02/2008
3Non-alcoholic Fatty Liver Disease
01/2020 - 09/2007
3Arteriosclerosis
01/2015 - 04/2004
3Vascular Remodeling
04/2011 - 06/2002
3Body Weight (Weight, Body)
03/2010 - 02/2004
2Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2021 - 03/2010
2Hyperlipidemias (Hyperlipidemia)
11/2021 - 10/2016
2Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
09/2020 - 09/2007
2Chronic Renal Insufficiency
08/2017 - 01/2017
2Atherosclerosis
10/2016 - 01/2013
2Arthritis (Polyarthritis)
10/2016 - 01/2013
2Cicatrix (Scar)
05/2013 - 02/2012
2Left Ventricular Dysfunction
12/2012 - 11/2011
2Stroke (Strokes)
01/2011 - 06/2002
1Cognitive Dysfunction
01/2022
1Dyslipidemias (Dyslipidemia)
11/2021
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2021
1Weight Loss (Weight Reduction)
01/2021
1Thrombotic Microangiopathies
07/2020
1Hemophilia A (Haemophilia)
07/2020
1Hyperhomocysteinemia
12/2019
1Death (Near-Death Experience)
01/2019
1Adenocarcinoma
01/2019
1Fatty Liver
12/2018

Drug/Important Bio-Agent (IBA)

43Plasminogen Activator Inhibitor 1IBA
11/2021 - 05/2002
28Plasminogen Activators (Plasminogen Activator)IBA
01/2021 - 05/2002
9Proteins (Proteins, Gene)FDA Link
08/2017 - 03/2005
9Tissue Plasminogen Activator (Alteplase)FDA Link
02/2014 - 06/2002
6CollagenIBA
08/2017 - 09/2010
5Transforming Growth Factors (Transforming Growth Factor)IBA
01/2021 - 03/2006
5Plasminogen InactivatorsIBA
08/2017 - 08/2002
5NG-Nitroarginine Methyl Ester (L-NAME)IBA
01/2015 - 06/2002
4TM5441IBA
01/2021 - 11/2013
4AcetyltransferasesIBA
01/2019 - 01/2012
4MicroRNAs (MicroRNA)IBA
08/2017 - 05/2012
3Angiotensin IIIBA
08/2017 - 04/2011
3Extracellular Matrix ProteinsIBA
08/2017 - 01/2013
3Transcription Factors (Transcription Factor)IBA
01/2017 - 11/2016
3arginine methyl esterIBA
01/2015 - 04/2011
3tiplaxtininIBA
06/2012 - 02/2005
3AngiotensinsIBA
12/2006 - 10/2003
3AldosteroneIBA
12/2006 - 05/2002
3PlasminogenIBA
04/2004 - 05/2002
2Biomarkers (Surrogate Marker)IBA
01/2022 - 11/2021
2GadoliniumIBA
01/2021 - 08/2017
2SugarsIBA
01/2021 - 12/2018
2von Willebrand FactorIBA
07/2020 - 04/2006
2CholesterolIBA
12/2018 - 10/2016
2Insulin (Novolin)FDA Link
11/2017 - 03/2006
2RNA (Ribonucleic Acid)IBA
08/2017 - 01/2016
2Scarlet Red (Sudan IV)IBA
10/2016 - 01/2013
2AntigensIBA
07/2014 - 02/2014
2Nitric Oxide Synthase (NO Synthase)IBA
11/2013 - 06/2002
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2013 - 02/2004
2CytokinesIBA
05/2013 - 09/2007
2Transforming Growth Factor beta (TGF-beta)IBA
09/2010 - 03/2006
2Messenger RNA (mRNA)IBA
03/2010 - 02/2004
2Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
02/2008 - 12/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2007 - 04/2004
2Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
12/2006 - 05/2002
2ThrombinFDA Link
04/2006 - 06/2005
2FibrinolysinFDA Link
09/2002 - 05/2002
1Particulate MatterIBA
10/2021
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
10/2021
1Caspase 3 (Caspase-3)IBA
10/2021
1Environmental Pollutants (Pollutants, Environmental)IBA
10/2021
1Perilipin-1IBA
01/2021
1Sterol Esterase (Hormone-Sensitive Lipase)IBA
01/2021
1Lipase (Acid Lipase)FDA Link
01/2021
1Biological ProductsIBA
01/2021
1Lisinopril (Prinivil)FDA LinkGeneric
09/2020
1Letrozole (Femara)FDA LinkGeneric
09/2020
1AnticoagulantsIBA
07/2020
1Hemostatics (Antihemorrhagics)IBA
07/2020
1Factor V (Coagulation Factor V)IBA
07/2020
1IntegrinsIBA
12/2019
1Histones (Histone)IBA
01/2019
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2019
1Choline (Choline Chloride)IBA
12/2018
1Methionine (L-Methionine)FDA Link
12/2018

Therapy/Procedure

4Therapeutics
12/2018 - 02/2009
4Cell- and Tissue-Based Therapy (Cell Therapy)
12/2012 - 05/2007
3Percutaneous Coronary Intervention
12/2012 - 01/2010
2Oral Administration
01/2015 - 06/2012
2Transjugular Intrahepatic Portasystemic Shunt
09/2002 - 05/2002
1Fat-Restricted Diet (Diet, Fat Restricted)
01/2021
1Diet Therapy (Therapy, Diet)
01/2021